In this room are exposed some important painting of schools outside Bologna.

The most important work is the polyptich made by Giotto for the Santa Maria degli Angeli church: the only signed by the Florentine master in Bologna, unica opera firmata del maestro fiorentino a Bologna, usually dated to 1330 circa.

Beside this artwork, it can be found others Umbrian and Tuscan works, like the Crucifix of Rinaldo di Ranuccio, signed and dated 1265, the Last Supper of the senese Andrea di Bartolo, an interesting small wood table of an anonymous florentine called Maestro della Misericordia which in the second half of the XIVth century seems to be aware of the new Giotto style, and a Madonna with Child by the late gothic Florentine painter Lorenzo Monaco.