In this room we see the artistic production of the early Bolognese Renaissance, with the Madonna enthroned with Child with St. Petronius and John Evangelist adored by the donor Alberto Cattani aka Merchants Altarpiece, (1474) by Francesco del Cossa, which occupy the entire right wall.

On the opposite wall are displayed a small wood table with Saint Michael Archangel, by Ercole de’ Roberti and, of the same artist, the preciuos fragment with Mary of Magdalen crying, the only surviving pating of the famous decoration of the della Garganelli Chapel in the St. Peter Church, begun by del Cossa and finished by Ercole (1479-1483), then destroyed at the end of the XVIth century.